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Invitrogen
Osteocalcin Polyclonal Antibody
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Osteocalcin Antibody (PA5-78871) in IHC (P)
Immunohistochemistry analysis of Osteocalcin on paraffin-embedded rat tibia tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Osteocalcin polyclonal antibody (Product# PA5-78871) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C)... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-78871
应用
建议稀释比
已发表文章
产品规格
种属反应
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived rat Osteocalcin recombinant protein (Position: Y50-V99).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - IHC: rat tibia tissue. Flow: L6 cell.
靶标信息
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin); Bone Gla protein; bone Gla-protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; PMF1; RP11-54H19.5
基因别名: Bglap; Bglap2; Bgp; Bgpr; Bgpra
UniProt ID: (Rat) P04640
Entrez Gene ID: (Rat) 25295
ossification
osteoblast differentiation
osteoblast development
aging
cell aging
response to mechanical stimulus
response to gravity
response to inorganic substance
response to zinc ion
response to organic cyclic compound
response to activity
regulation of bone mineralization
biomineral tissue development
response to nutrient levels
response to vitamin K
response to vitamin D
response to testosterone
response to hydroxyisoflavone
odontogenesis
response to drug
response to estrogen
response to ethanol
response to glucocorticoid
bone development
cellular response to vitamin D
cellular response to growth factor stimulus
cellular response to BMP stimulus
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
