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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HT1080 whole cell, human U20S whole cell, human Caco-2 whole cell, human Hela whole cell, human A549 whole cell, rat lung tissue, mouse lung tissue. IHC: human rectal cancer tissue, rat lung tissue. ICC/IF: A549 cell. Flow: A549 cell.
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: caveolae; Caveolin-2; MGC12294; Phospho-CAV2
基因别名: AI447843; CAV2
UniProt ID: (Mouse) Q9WVC3, (Rat) Q2IBC5
Entrez Gene ID: (Mouse) 12390, (Rat) 363425