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Invitrogen
FGF8 Polyclonal Antibody
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FGF8 Antibody (PA5-79258) in WB
Western blot analysis of FGF8 in Lane 1: rat ovary tissue lysate, Lane 2: human HeLa whole cell lysate, Lane 3: human placenta tissue lysate using 50 µg (reducing conditions) per well. Electrophoresis was performed on 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours and protein was transferred to a nitrocellulose membrane at 150mA for 50-90 minutes. Sample was blocked with 5% Non-fat Milk/TBS for 1.5 hours at room temperature, incubated with FGF8 polyclonal antibody (Product # PA5-79258) at a dilution of 0.5 µg/... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79258
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human FGF8 recombinant protein (Position: Q23-R233).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat ovary tissue, human Hela whole cell, human placenta tissue.
靶标信息
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: androgen-induced; androgen-induced growth factor; FGF; Fibroblast growth factor; fibroblast growth factor 6c; fibroblast growth factor 8 (androgen-induced); heparin-binding growth factor 8; MGC149376; unnamed protein product
基因别名: AIGF; FGF-8; Fgf6c; HBGF-8; HH6; KAL6
UniProt ID: (Human) P55075, (Mouse) P37237
Entrez Gene ID: (Human) 2253, (Rat) 29349, (Mouse) 14179
metanephros development
mesonephros development
outflow tract septum morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
response to oxidative stress
signal transduction
gastrulation
motor neuron axon guidance
positive regulation of cell proliferation
gonad development
fibroblast growth factor receptor signaling pathway
response to xenobiotic stimulus
anatomical structure morphogenesis
dorsal/ventral pattern formation
positive regulation of gene expression
forebrain neuron development
central nervous system neuron development
neurogenesis
regulation of cell migration
dorsal/ventral axon guidance
odontogenesis
positive regulation of MAPK cascade
positive regulation of cell differentiation
positive chemotaxis
negative regulation of cardiac muscle tissue development
bone development
neuroepithelial cell differentiation
dopaminergic neuron differentiation
MAPK cascade
patterning of blood vessels
branching involved in ureteric bud morphogenesis
organ induction
kidney development
neural plate morphogenesis
heart looping
blood vessel remodeling
heart morphogenesis
outflow tract morphogenesis
determination of left/right symmetry
heart development
mesodermal cell migration
embryo development ending in birth or egg hatching
telencephalon development
pallium development
subpallium development
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
signal transduction involved in regulation of gene expression
lung development
male genitalia development
thyroid gland development
otic vesicle formation
midbrain-hindbrain boundary development
embryonic heart tube development
limb morphogenesis
embryonic hindlimb morphogenesis
aorta morphogenesis
inner ear morphogenesis
regulation of odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell fate commitment
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of mitotic nuclear division
positive regulation of organ growth
generation of neurons
embryonic neurocranium morphogenesis
forebrain morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
pharyngeal system development
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
lung morphogenesis
branching involved in salivary gland morphogenesis
positive regulation of ERK1 and ERK2 cascade
cell migration involved in mesendoderm migration
larynx morphogenesis
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