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Invitrogen
FZD3 Polyclonal Antibody
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FZD3 Antibody (PA5-79289) in IHC (P)
Immunohistochemistry analysis of FZD3 on paraffin-embedded human mammary cancer tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with FZD3 polyclonal antibody (Product# PA5-79289) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). D... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79289
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human FZD3 (MPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFL).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human SK-OV-3 cell, human Jurkat cell. IHC: human colon cancer tissue, human mammary cancer tissue, mouse kidney tissue, rat kidney tissue.
靶标信息
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: frizzled 3; frizzled family receptor 3; Frizzled-3; Fz-3; hFz3; mFz3
基因别名: AU020229; D930050A07Rik; Fz3; FZD3
UniProt ID: (Mouse) Q61086
Entrez Gene ID: (Mouse) 14365, (Rat) 266715
establishment of planar polarity
neuron migration
neural tube closure
positive regulation of neuroblast proliferation
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
canonical Wnt signaling pathway
sympathetic ganglion development
commissural neuron axon guidance
negative regulation of execution phase of apoptosis
hair follicle development
brain development
response to drug
response to electrical stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
