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          • Primary Antibodies ›
          • MGST1 Antibodies

          Invitrogen

          MGST1 Polyclonal Antibody

          2 Published Figures
          1 Reference
          View all (13) MGST1 antibodies

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          Cite MGST1 Polyclonal Antibody

          Additional Information:

          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • Antibody Testing Data (3)
          • Published Figures (2)
          MGST1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MGST1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          MGST1 Antibody (PA5-79670) in IHC (P)

          Immunohistochemistry (Paraffin) analysis of MGST1 in paraffin-embedded section of human pancreas cancer tissue using MGST1 Polyclonal Antibody (Product # PA5-79670). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution overnig... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          MGST1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MGST1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MGST1 Antibody in Western Blot (WB)
          MGST1 Antibody in Western Blot (WB)
          MGST1 Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          MGST1 Polyclonal Antibody

          Product Details

          PA5-79670

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1-0.5 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          2-5 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide corresponding to a sequence at the N-terminus of human MGST1 (42-75aa KVFANPEDCVAFGKGENAKKYLRTDDRVERVRRA).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          500 µg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 4mg trehalose, 0.9mg NaCl, 0.2mg Na2PO4

          Contains

          no preservative

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2746785

          Product Specific Information

          Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

          Positive Control - WB: human RT4 whole cell, human A549 whole cell, human U251 whole cell, human SiHa whole cell, rat testis tissue, rat liver tissue, mouse liver tissue, mouse testis tissue. IHC: human pancreas cancer tissue, human stomach cancer tissue.

          Target Information

          The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: glutathione S-transferase; glutathione S-transferase 12; human and rat liver mic GST homolog; MGC14525; MGST1; microsomal GST-1; microsomal GST-I; peritoneal metastasis associated long noncoding RNA; unnamed protein product

          View more View less

          Gene Aliases: 1500002K10Rik; Gst; GST12; MGST; MGST-I; PMAN

          View more View less

          UniProt ID: (Human) P10620, (Mouse) Q91VS7, (Rat) P08011

          View more View less

          Entrez Gene ID: (Human) 4257, (Mouse) 56615, (Rat) 171341

          View more View less

          Function(s)
          glutathione transferase activity glutathione peroxidase activity protein binding identical protein binding glutathione binding
          Process(es)
          glutathione metabolic process response to xenobiotic stimulus response to lipopolysaccharide glutathione transport cellular response to lipid hydroperoxide cellular oxidant detoxification Leydig cell differentiation
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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