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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat testis tissue, mouse lung tissue, 293T whole cell. IHC: mouse brain tissue, rat brain tissue, human intestinal cancer tissue. Flow: HeLa cell.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha-7; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; multicatalytic proteinase subunit K; Proteasome component C8; Proteasome subunit alpha type-3; Proteasome subunit alpha-7; proteasome subunit C8; Proteasome subunit K; PSA3
基因别名: HC8; Lmpc8; PSC8; PSMA3; Psma3l
UniProt ID: (Mouse) O70435, (Rat) P18422
Entrez Gene ID: (Mouse) 19167, (Rat) 29670