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Invitrogen
Regucalcin Polyclonal Antibody
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Regucalcin Antibody (PA5-79924) in IHC (P)
Immunohistochemistry analysis of Regucalcin on paraffin-embedded mouse liver tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Regucalcin polyclonal antibody (Product# PA5-79924) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C)... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79924
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human Regucalcin (YSVDAFDYDLQTGQISNRRSVYKLEKEEQIPD).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat liver tissue, mouse liver tissue, human SMMC-7721 whole cell. IHC: mouse liver tissue, rat kidney tissue, rat liver tissue.
靶标信息
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gluconolactonase; GNL; RC; Regucalcin; Senescence marker protein 30; SMP-30
基因别名: AI265316; GNL; Rc; Reguc; RGN; SMP30
UniProt ID: (Rat) Q03336, (Mouse) Q64374
Entrez Gene ID: (Rat) 25106, (Mouse) 19733
kidney development
liver development
negative regulation of protein phosphorylation
negative regulation of protein kinase activity
cellular calcium ion homeostasis
spermatogenesis
aging
positive regulation of triglyceride biosynthetic process
positive regulation of glucose metabolic process
positive regulation of phosphatase activity
L-ascorbic acid biosynthetic process
negative regulation of phosphoprotein phosphatase activity
positive regulation of ATPase activity
negative regulation of GTPase activity
negative regulation of apoptotic process
positive regulation of GTPase activity
negative regulation of nitric oxide biosynthetic process
positive regulation of fatty acid biosynthetic process
negative regulation of epithelial cell proliferation
regulation of calcium-mediated signaling
negative regulation of cyclic-nucleotide phosphodiesterase activity
liver regeneration
negative regulation of sperm motility
positive regulation of superoxide dismutase activity
positive regulation of calcium-transporting ATPase activity
negative regulation of RNA biosynthetic process
negative regulation of bone development
positive regulation of proteolysis involved in cellular protein catabolic process
negative regulation of calcium-dependent ATPase activity
negative regulation of DNA catabolic process
positive regulation of dUTP diphosphatase activity
negative regulation of leucine-tRNA ligase activity
negative regulation of DNA biosynthetic process
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