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Invitrogen
Band 3 Polyclonal Antibody
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Band 3 Antibody (PA5-80030) in IHC (P)
Immunohistochemical analysis of SLC4A1 in paraffin-embedded section of human placenta tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution ) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-SLC4A1 antibody (Product # PA5-80030) overnight at 4°C. DyLight®488 Conjugated Goat Anti-... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-80030
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human SLC4A1 (Position: E28-N365).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human K562 whole cell, human T-47D whole cell. IHC: Rat Kidney tissue, Human Placenta tissue, Mouse Kidney tissue. IHC: Human Placenta tissue, human kidney tissue. Flow: K562 cells.
靶标信息
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AE 1; Anion exchange protein 1; anion exchanger 1; Band 3 anion transport protein; CAMP; CD233; erythrocyte membrane protein band 3; MEB3; MGC116750; MGC116753; MGC126619; MGC126623; Solute carrier family 4 member 1; Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3); ZNF828
基因别名: AE1; CD233; DI; Empb3; EPB3; l11Jus51; SLC4A1
UniProt ID: (Mouse) P04919, (Rat) P23562
Entrez Gene ID: (Mouse) 20533, (Rat) 24779
actin binding
transporter activity
inorganic anion exchanger activity
protein binding
protein C-terminus binding
anion transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
anion:anion antiporter activity
enzyme binding
ankyrin binding
protein homodimerization activity
secondary carrier transporter
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
