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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Rat Testis Tissue, Mouse Brain Tissue, Human Placenta Tissue, 22RV1 whole cell, SMMC whole cell. IHC: rat brain tissue, human lung cancer tissue. Flow: U20S cell, THP-1 cell.
ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZP434C131; EC:2.7.11.1; FLJ90566; Serine/threonine-protein kinase ULK3; Unc-51-like kinase 3
基因别名: 1200015E14Rik; ULK3
UniProt ID: (Mouse) Q3U3Q1, (Rat) D3ZHP7
Entrez Gene ID: (Mouse) 71742, (Rat) 691171