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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human 293T whole cell, human K562 whole cell, human Jurkat whole cell, rat brain tissue, rat liver tissue, mouse brain tissue, mouse liver tissue. IHC: rat kidney tissue, human placenta tissue, human colon cancer tissue, human mammary cancer tissue IHC-F: rat intestine tissue, human placenta tissue, mouse intestine tissue. ICC/IF: NIH3T3 cell. Flow: THP-1 cell.
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA repair protein XRCC1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1
基因别名: Xrcc-1; XRCC1
UniProt ID: (Rat) Q9ESZ0, (Mouse) Q60596
Entrez Gene ID: (Rat) 84495, (Mouse) 22594