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Invitrogen
YES1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-80243
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human Yes1 (7-35aa KENKSPAIKYRPENTPEPVSTSVSHYGAE).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human U20S whole cell, human CACO-2 whole cell, human A431 whole cell, human HepG2 whole cell, human MCF-7 whole cell, human PC-3 whole cell. IHC: human mammary cancer tissue.
靶标信息
YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: c-Src; cellular yes-1 protein; EC 2.7.10.2; p60-Src; pp60c-src; proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; unnamed protein product; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; Yamaguchi sarcoma oncogene; YES1 proto-oncogene, Src family tyrosine kinase
基因别名: c-yes; HsT441; P61-YES; Yes
UniProt ID: (Human) P07947
Entrez Gene ID: (Human) 7525
negative regulation of inflammatory response to antigenic stimulus
transmembrane receptor protein tyrosine kinase signaling pathway
cell differentiation
T cell costimulation
protein modification process
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of vascular permeability
ephrin receptor signaling pathway
leukocyte migration
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