Search

  • 联系我们
  • 货号直购

Invitrogen

HDAC6 Polyclonal Antibody

查看其他27个HDAC6抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
HDAC6 Polyclonal Antibody

产品信息

PA5-86320

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
-

免疫组化（石蜡） (IHC (P))

1:50-1:200
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to the N-terminal of Human HDAC6.
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2803103

产品详细信息

Purity is > 95% by SDS-PAGE.

靶标信息

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: E3 ubiquitin-protein ligase HDAC6; FLJ16239; HDA6; histone deacetylase 5; histone deacetylase 6; histone deacetylase mHDA2; mHDA2; Protein deacetylase HDAC6; scurfy candidate 6; Tubulin-lysine deacetylase HDAC6

查看更多 收起

基因别名: Hd6; Hdac5; HDAC6; JM21; KIAA0901; mHDA2; Sfc6

查看更多 收起

UniProt ID: (Mouse) Q9Z2V5

查看更多 收起

Entrez Gene ID: (Rat) 84581, (Mouse) 15185

查看更多 收起

功能
core promoter binding histone deacetylase activity protein binding beta-catenin binding microtubule binding zinc ion binding hydrolase activity polyubiquitin binding ubiquitin protein ligase binding histone deacetylase binding tubulin deacetylase activity alpha-tubulin binding ubiquitin binding tau protein binding beta-tubulin binding misfolded protein binding Hsp90 protein binding dynein complex binding actin binding histone deacetylase activity (H3-K14 specific) NAD-dependent histone deacetylase activity (H3-K14 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity (H4-K16 specific) metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) NAD-dependent histone deacetylase activity (H3-K18 specific) histone modifying enzyme
参与通路
protein polyubiquitination regulation of protein phosphorylation response to amphetamine protein deacetylation ubiquitin-dependent protein catabolic process misfolded or incompletely synthesized protein catabolic process intracellular protein transport negative regulation of microtubule depolymerization metabolic process positive regulation of cell proliferation response to toxic substance positive regulation of signal transduction response to organic substance regulation of receptor activity positive regulation of epithelial cell migration regulation of mitochondrion organization positive regulation of receptor biosynthetic process negative regulation of neuron projection development macroautophagy histone deacetylation axonal transport of mitochondrion neuron differentiation lysosome localization cellular response to oxidative stress peptidyl-lysine deacetylation response to immobilization stress cellular response to topologically incorrect protein regulation of gene expression, epigenetic ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway protein complex disassembly negative regulation of protein complex disassembly regulation of fat cell differentiation negative regulation of proteolysis negative regulation of axon extension involved in axon guidance positive regulation of dendrite morphogenesis response to corticosterone response to misfolded protein positive regulation of synaptic transmission, glutamatergic regulation of establishment of protein localization cellular response to hydrogen peroxide regulation of microtubule cytoskeleton organization aggresome assembly polyubiquitinated misfolded protein transport Hsp90 deacetylation response to growth factor cellular response to misfolded protein cellular response to parathyroid hormone stimulus response to dexamethasone positive regulation of chaperone-mediated protein complex assembly tubulin deacetylation positive regulation of tubulin deacetylation positive regulation of hydrogen peroxide-mediated programmed cell death negative regulation of protein acetylation positive regulation of oxidative stress-induced neuron death transcription, DNA-templated regulation of transcription, DNA-templated chromatin modification mitochondrion localization mitophagy in response to mitochondrial depolarization
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持