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Invitrogen
Ezrin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-87489
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.41 mg/mL
规格
141 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RLQDYEEKTK KAERELSEQI QRALQLEEER KRAQEEAERL EADRMAALRA KEELERQAVD QIKSQEQLAA ELAEYTAKIA LLEEARRRKE DEVEEWQHRA KEAQDDLVKT KEELHLVMTA P; Positive Samples: M21, SW480, U-251MG, 293T, Mouse intestine, Mouse brain, Rat brain; Cellular Location: Apical cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cell cortex, cytoskeleton, microvillus membrane, ruffle membrane
靶标信息
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytovillin; DKFZp762H157; EZRI; Ezrin; FLJ26216; MGC1584; p81; villin 2; Villin-2
基因别名: AW146364; Ezr; p81; R75297; Vil2
UniProt ID: (Mouse) P26040, (Rat) P31977
Entrez Gene ID: (Mouse) 22350, (Rat) 54319
intestinal D-glucose absorption
sphingosine-1-phosphate signaling pathway
regulation of cell shape
positive regulation of gene expression
microvillus assembly
actin cytoskeleton reorganization
receptor internalization
regulation of microvillus length
establishment or maintenance of apical/basal cell polarity
positive regulation of multicellular organism growth
filopodium assembly
phosphatidylinositol-mediated signaling
positive regulation of protein secretion
actin filament bundle assembly
establishment of endothelial barrier
positive regulation of establishment of protein localization to plasma membrane
regulation of organelle assembly
terminal web assembly
positive regulation of protein localization to early endosome
positive regulation of cellular protein catabolic process
positive regulation of early endosome to late endosome transport
leukocyte cell-cell adhesion
membrane to membrane docking
epithelial cell differentiation
establishment of epithelial cell apical/basal polarity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
