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Invitrogen
SH3BP2 Polyclonal Antibody
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SH3BP2 Antibody (PA5-87739) in WB
Western blot analysis of SH3BP2 in extracts of various cell lines. Samples were incubated with SH3BP2 Polyclonal antibody (Product # PA5-87739) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-87739
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_0011161531)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.27 mg/mL
规格
227 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VPEAMARPAV LPRPEKPQLP HLQRSPPDGQ SFRSFSFEKP RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ DGLYCIRNSS TKSGKVLVVW DETSNKVRNY RIFEKDSKFY LEGEVLFVSV GSMVEHYHTH VLPSHQSLLL RHPYGYTGPR; Positive Samples: A549, Mouse spleen, Mouse lung
靶标信息
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
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