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Invitrogen
CACNA2D3 Polyclonal Antibody
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CACNA2D3 Antibody (PA5-87802) in WB
Western blot analysis of CACNA2D3 in extracts of various cell lines. Samples were incubated with CACNA2D3 Polyclonal antibody (Product # PA5-87802) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-87802
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.52 mg/mL
规格
52 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LYDYQAMCRA NKESSDGAHG LLDPYNAFLS AVKWIMTELV LFLVEFNLCS WWHSDMTAKA QKLKQTLEPC DTEYPAFVSE RTIKETTGNI ACEDCSKSFV IQQIPSSNLF MVVVDSSCLC ESVAPITMAP IEIRYNESLK C; Positive Samples: U-87 MG, HeLa, Hep G2, Mouse brain, Rat brain; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 2 delta-3; alpha2delta3; calcium channel, voltage dependent, alpha2/delta subunit 3; calcium channel, voltage-dependent, alpha 2/delta 3 subunit; CaV alpha2delta3; Voltage-dependent calcium channel subunit alpha-2/delta-3; Voltage-gated calcium channel subunit alpha-2/delta-3
基因别名: Cacna2d3; Cacnad3
UniProt ID: (Rat) Q8CFG5, (Mouse) Q9Z1L5
Entrez Gene ID: (Rat) 306243, (Mouse) 12294
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