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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TLEYVSSLDF WYCKRCKANI GGHRSSCSFC KNPREVTEAK QELITYPQPQ KTSIPAPLEK QPNQPLRPAD KEPEPRKREE GQESRLGHQK REAERYLPPS RREGPTFRRD RERESWSGET RQDGESKTIM LKRIYRSTPP EVIVEVLEPY VRLTTANVRI IKNRTGPMGH TYGFIDLDSH AEALRVVKIL QNLDPPFSID GKMVAVNLAT GKRRNDSGDH SDHMHYYQGK KYFRDRRGGG R; Positive Samples: A-549, 293T, HeLa, HepG2; Cellular Location: Nucleus
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ETK2; HEK2; TYRO6