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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LREISSAAAH SQPFAWKKKA LIIIWAKVLQ PHPVTPSDTE TRWQEDLFFS VGNMIPTINH TILFELLKSL EASGLFIQLL MALPTTICHA ELERFLEHVT VDTSAEDVAF FLDVWWEVMK HKGHPQDPLL SQFSAMAHKY LPALDEFPHP PKRLRSDPDA CPTMPLLAML LRGLTQIQSR ILGPGRKCCA LANLADMLTV FALTEDDPQE VSATVYLDKL ATVISVWNSD TQNPYHQQAL AEKVKEAERD VSLTSLAKLP SETIFVGCEF LHHLLREWGE ELQAVLRSSQ GTSYDSYRLC D; Positive Samples: HeLa, MCF-7, SH-SY5Y, Jurkat, Mouse brain, Mouse kidney, Mouse liver; Cellular Location: Cytoplasm, Nucleus, gem, nucleolus
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies. The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp434B131; DKFZp434D174; gem-associated protein 4
基因别名: 4932415L08Rik; AU015359
Entrez Gene ID: (Mouse) 276919