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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LPKSALFSES QKAVELGDEL QIDAIDDQKC DILVQEELLA SPKKLLEDTL FPSSKKLKKD NQESSDAELS SSEYIKTDLD AMDIKGQESS SDQEQVDVES IDFSKENKMD MTSPEQSRNV LQFTEEKEAF ISEEEIAKYM KRGKGKYYCK ICCCRAMKKG AVLHHLVNKH NVHSPYKCTI CGKAFLLESL LKNHVAAHGQ SLLKCPRCNF ESNFPRGFKK HLTHCQSRHN EEANKKLMEA LEPPLEEQQI; Positive Samples: U-87MG, A-431, Jurkat ; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle
Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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