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Invitrogen
USH1C Polyclonal Antibody
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USH1C Antibody (PA5-88622) in WB
Western blot analysis of USH1C in extracts of various cell lines. Samples were incubated with USH1C Polyclonal antibody (Product # PA5-88622) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-88622
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human USH1C (NP_0012846931)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.83 mg/mL
规格
183 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VDFSNLDHKE GRELFMTDRE RLAEARQREL QRQELLMQKR LAMESNKILQ EQQEMERQRR KEIAQKAAEE NERYRKEMEQ IVEEEEKFKK QWEEDWGSKE QLLLPKTITA EVHPVPLRKP KYDQGVEPEL EPADDLDGGT EEQGEQDFRK YEEGFDPYSM FTPEQIMGKD VRLLRIKKEG SLDLALEGGV DSPIGKVVVS AVYERGAAER HGGIVKGDEI MAINGKIVTD YTLAEAEAAL QKAWNQGGDW IDLVVAVCPP KEYDDELTFF; Positive Samples: 293T, HeLa, Mouse kidney, Mouse intestine, Rat kidney; Cellular Location: Cytoplasm, cytoskeleton, cytosol
靶标信息
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Harmonin; harmonin a1; PDZ domain-containing protein; PDZ-73 protein; Usher syndrome 1C homolog; Usher syndrome type-1C protein homolog
基因别名: 2010016F01Rik; harmonin; Ush1c
UniProt ID: (Mouse) Q9ES64
Entrez Gene ID: (Rat) 308596, (Mouse) 72088
G2/M transition of mitotic cell cycle
sensory perception of sound
parallel actin filament bundle assembly
inner ear morphogenesis
auditory receptor cell differentiation
photoreceptor cell maintenance
neuromuscular process controlling balance
sensory perception of light stimulus
equilibrioception
actin filament bundle assembly
inner ear receptor stereocilium organization
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