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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MGDGAVKQGF LYLQQQQTFG KKWRRFGASL YGGSDCALAR LELQEGPEKP RRCEAARKVI RLSDCLRVAE AGGEASSPRD TSAFFLETKE RLYLLAAPAA ERGDWVQAIC LLAFPGQRKE LSGPEGKQSR PCMEENELYS SAVTVGPHKE FAVTMRPTEA SERCHLRGSY TLRAGESALE LWGGPEPGTQ LYDWPYRFLR RFGRDKVTFS FEAGRRCVSG EGNFEFETRQ GNEIFLALEE AISAQKNAAP ATPQPQPATI; Positive Samples: THP-1, Mouse lung
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: docking protein 2, 56kD; docking protein 2, 56kDa; dok-related protein; downstream of tyrosine kinase 2; hematopoietic cell-specific signaling molecule which is phosporylated in response to cytokine stimulation; interacts with rasGAP; IL-four receptor-interacting protein; p56(dok-2); Tek/Tie2 binding protein; unnamed protein product
基因别名: dok-R; DokR; Frip; p56DOK; p56dok-2
UniProt ID: (Human) O60496, (Mouse) O70469
Entrez Gene ID: (Human) 9046, (Mouse) 13449