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Invitrogen
AFG3L2 Polyclonal Antibody
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AFG3L2 Antibody (PA5-90436) in IHC (P)
Immunohistochemistry analysis of AFG3L2 in paraffin-embedded human colon carcinoma. Samples were incubated with AFG3L2 Polyclonal antibody (Product # PA5-90436) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-90436
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 538-797 of human AFG3L2 (NP_0067872)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.65 mg/mL
规格
65 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DSINQKHFEQ AIERVIGGLE KKTQVLQPEE KKTVAYHEAG HAVAGWYLEH ADPLLKVSII PRGKGLGYAQ YLPKEQYLYT KEQLLDRMCM TLGGRVSEEI FFGRITTGAQ DDLRKVTQSA YAQIVQFGMN EKVGQISFDL PRQGDMVLEK PYSEATARLI DDEVRILIND AYKRTVALLT EKKADVEKVA LLLLEKEVLD KNDMVELLGP RPFAEKSTYE EFVEGTGSLD EDTSLPEGLK DWNKEREKEK EEPPGEKVAN; Positive Samples: LO2, 293T, HeLa, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Mouse pancreas; Cellular Location: Mitochondrion membrane, Multi-pass membrane protein
靶标信息
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AFG3 ATPase family member 3-like 2; AFG3(ATPase family gene 3)-like 2; AFG3-like protein 2; FLJ25993; Mitochondrial inner membrane m-AAA protease component AFG3L2
基因别名: 2310036I02Rik; Afg3l2; AW260507; Emv66; par
UniProt ID: (Mouse) Q8JZQ2
Entrez Gene ID: (Mouse) 69597, (Rat) 307350
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