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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PTIISESFQK ALEKGIEILT DMSRPVELSD RETLLNSATT SLNSKVVSQY SSLLSPMSVN AVMKVIDPAT ATSVDLRDIK IVKKLGGTID DCELVEGLVL TQKVSNSGIT RVEKAKIGLI QFCLSAPKTD MDNQIVVSDY AQMDRVLREE RAYILNLVKQ IKKTGCNVLL IQKSILRDAL SDLALHFLNK MKIMVIKDIE REDIEFICKT IGTKPVAHID QFTADMLGSA ELAEEVNLNG SGKLLKITGC ASPGKTVTIV V; Positive Samples: MCF7, THP-1, Mouse spleen; Cellular Location: Cytoplasm, Melanosome, centrosome, cilium basal body, cytoskeleton, microtubule organizing center
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A45; CCT-delta; chaperonin subunit 4 (delta); T complex protein 1, delta; T-complex protein 1 subunit delta; TCP-1 delta; TCP-1-delta
基因别名: 2610204B21Rik; A45; C78323; Cct4; Cctd
UniProt ID: (Mouse) P80315, (Rat) Q7TPB1
Entrez Gene ID: (Mouse) 12464, (Rat) 29374