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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: VSDLPRQWTP KNTSCDSGLG CQDTLMLIES GPQVSLVLSK GCTEAKDQEP RVTEHRMGPG LSLISYTFVC RQEDFCNNLV NSLPLWAPQP PADPGSLRCP VCLSMEGCLE GTTEEICPKG TTHCYDGLLR LRGGGIFSNL RVQGCMPQPV CNLLNGTQEI GPVGMTENCD MKDFLTCHRG TTIMTHGNLA QEPTDWTTSN TEMCEVGQVC QETLLLLDVG LTSTLVGTKG CSTVGAQNSQ KTTIHSAPPG V; Positive Samples: BT-474; Cellular Location: Cell membrane, GPI-anchor, Lipid-anchor
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD177; CD177 antigen
基因别名: 1190003K14Rik; Cd177; Pdp3
UniProt ID: (Mouse) Q8R2S8
Entrez Gene ID: (Mouse) 68891