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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Samples: 293T, HeLa, HepG2, Raji, Mouse lung, Mouse heart; Cellular Location: Membrane, Single-pass type I membrane protein
Immunogen sequence: ESELPLECAT HFVRIKSLVD DAKFPEPNFW SNWSSWEEVS VQDSTGQDIL FVFPKDKLVE EGTNVTICYV SRNIQNNVSC YLEGKQIHGE QLDPHVTAFN L
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IL-31 receptor subunit beta; IL-31R subunit beta; IL-31R-beta; IL-31RB; Interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin receptor; oncostatin-M specific receptor subunit beta; Oncostatin-M-specific receptor subunit beta
基因别名: Osmr; OSMRB
UniProt ID: (Mouse) O70458
Entrez Gene ID: (Mouse) 18414