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Invitrogen
Annexin A2 Polyclonal Antibody
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Product Details
PA5-94968
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Annexin A2 (121-141aa RAEDGSVIDYELIDQDARDLY).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
0.9mg NaCl, 0.2mg Na2PO4, 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Testis Tissue, Rat Lung Tissue, Rat Ovary Tissue, MCF-7 Cell, SMMC Cell, A549 Cell, JURKAT Cell, mouse spleen tissue, mouse NIH/3T3 whole cell. IHC: Human Intestinal Cancer Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 33-kDa calcimedin; 33-kDa lymphocyte Ca<2+>- binding protein; 33kDa lymphocyte Ca<2+>- binding protein; 36-kDa calelectrin; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; epididymis secretory protein Li 270; epididymis secretory sperm binding protein; Lipocortin II; p36; PAP-IV; Placental anticoagulant protein IV; Protein I; unnamed protein product
Gene Aliases: ANX2; ANX2L4; ANXA2; AW215814; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV
UniProt ID: (Human) P07355, (Mouse) P07356, (Rat) Q07936
Entrez Gene ID: (Human) 302, (Mouse) 12306, (Rat) 56611
phosphatidylserine binding
protease binding
RNA binding
phospholipase inhibitor activity
serine-type endopeptidase inhibitor activity
calcium ion binding
protein binding
calcium-dependent phospholipid binding
phosphatidylinositol-4,5-bisphosphate binding
cytoskeletal protein binding
phospholipase A2 inhibitor activity
identical protein binding
S100 protein binding
calcium-dependent protein binding
cadherin binding involved in cell-cell adhesion
Rab GTPase binding
receptor activator activity
poly(A) RNA binding
actin filament binding
calcium-binding protein
angiogenesis
membrane raft assembly
positive regulation of receptor recycling
negative regulation of receptor internalization
membrane budding
cell adhesion
cell-matrix adhesion
positive regulation of plasminogen activation
response to activity
collagen fibril organization
lung development
positive regulation of vesicle fusion
negative regulation of low-density lipoprotein particle receptor catabolic process
osteoclast development
fibrinolysis
mRNA transcription from RNA polymerase II promoter
positive regulation of vacuole organization
positive regulation of exocytosis
positive regulation of transcription from RNA polymerase II promoter
regulation of neurogenesis
negative regulation of transport
positive regulation of multicellular organismal process
cell-cell adhesion
epithelial cell apoptotic process
positive regulation of low-density lipoprotein particle clearance
positive regulation of receptor-mediated endocytosis involved in cholesterol transport
positive regulation of plasma membrane repair
positive regulation of protein phosphorylation
body fluid secretion
negative regulation of catalytic activity
positive regulation of fibroblast proliferation
positive regulation of binding
protein heterotetramerization
cellular response to acid chemical
protein targeting to plasma membrane
negative regulation of receptor binding
positive regulation of receptor activity
regulation of fibrinolysis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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