Search
Invitrogen
Urokinase Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 1
Urokinase Antibody (PA5-95504) in WB
Western blot analysis of Urokinase in Lane 1: rat pancreas tissue lysates, Lane 2: mouse pancreas tissue lysates. Electrophoresis was performed with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V Resolving gel, Time: 2-3 hours), transferred to a nitrocellulose membrane and blocked using 5% Non-fat Milk/TBS (1.5 hrs at room temperature). Samples were incubated with Urokinase polyclonal antibody (Product # PA5-95504) using a 0.5 µg/mL dilution, followed by a goat anti-rabbit IgG-HRP at a dilution of 1:10,000, and developed with enhanced chemilum... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-95504
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human PLAU recombinant protein (Position: I179-L431).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat pancreas tissue, mouse pancreas tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: antagonist of uPA; CD87; HGNC:9052; plasminogen activator; U-plasminogen activator; uPA; UPAR; Urinary plasminogen activator, urokinase; URKR; Urokinase-type plasminogen activator
基因别名: Plau; u-PA; uPA; UPAM
UniProt ID: (Mouse) P06869
Entrez Gene ID: (Rat) 25619, (Mouse) 18792
angiogenesis
response to hypoxia
proteolysis
spermatogenesis
embryo implantation
positive regulation of cell proliferation
regulation of receptor activity
response to activity
smooth muscle cell migration
regulation of smooth muscle cell migration
positive regulation of smooth muscle cell migration
phosphorylation
regulation of cell adhesion mediated by integrin
response to hepatocyte growth factor
cellular response to hepatocyte growth factor stimulus
wound healing
regulation of cell proliferation
fibrinolysis
skeletal muscle tissue regeneration
response to hyperoxia
positive regulation of ovulation
neuron death
cellular response to lipopolysaccharide
cellular response to organic substance
cellular response to glucose stimulus
cellular response to hypoxia
cellular response to fluid shear stress
cellular response to staurosporine
regulation of smooth muscle cell-matrix adhesion
regulation of hepatocyte proliferation
positive regulation of reactive oxygen species metabolic process
plasminogen activation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
