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Invitrogen
S100A10 Polyclonal Antibody
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图: 1 / 24
S100A10 Antibody (PA5-95505) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of S100A10 in U2OS cells using S100A10 Polyclonal Antibody (Product # PA5-95505). Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and incubated with the primary antibody at 5 µg/mL. DyLight 488 conjugated goat anti-rabbit IgG was used as secondary antibody at 1:500 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-95505
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human S100A10 recombinant protein (Position: Q4-K94).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
4mg trehalose, 0.9mg NaCl, 0.2mg Na2PO4
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue, human A431 whole cell, human Hacat whole cell, human U87 whole cell, monkey lung tissue, rat PC-12 whole cell, mouse NIH/3T3 whole cell. IHC: human breast tissue, human intestinal diffuse large B-cell lymphoma tissue, human liver cancer tissue, human lung adenocarcinoma tissue, human ovarian serous adenocarcinoma tissue, human tonsil tissue. ICC/IF: U2OS cell. Flow: A431 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Annexin II; annexin II ligand; calcium binding protein A11 (calgizzarin); Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; MGC111133; MGC133268; Nerve growth factor-induced protein 42C; OTTHUMP00000015270; P PRSS26; p10 protein; p11; p11 subunit; Protein S100 A10; Protein S100-A10; S-100 related protein, clone 42C; S100 calcium binding protein A10 (calgizzarin); S100 calcium-binding protein A10
基因别名: 42C; AA409961; AL024248; CAL12; Cal1l; CLP11; p10; p11; S100a10
UniProt ID: (Rat) P05943, (Mouse) P08207
Entrez Gene ID: (Rat) 81778, (Mouse) 20194
regulation of cell growth
membrane raft assembly
membrane budding
response to antidepressant
regulation of cell differentiation
positive regulation of binding
protein heterotetramerization
positive regulation of stress fiber assembly
positive regulation of focal adhesion assembly
establishment of protein localization to plasma membrane
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of GTPase activity
cellular response to acid chemical
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