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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: FIGCRKVTGT LDANRSSYDV FQLEFNDGAY NIKDSTGKYW TVGSDSAVTS SGDTPVDFFF EFCDYNKVAI KVGGRYLKGD HAGVLKASAE TVDPASLWEY; Positive Samples: U-251MG, HeLa, NCI-H460, HepG2, SH-SY5Y, Mouse brain, Mouse spinal cord; Cellular Location: Cell junction, Cell projection, Cytoplasm, cytoskeleton, cytosol, filopodium, invadopodium, microvillus
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 55kDa actin-bundling protein; Fascin; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; Fascin1; fscn1 {ECO:0000250|UniProtKB:Q16658}; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); Singed-like protein
Gene Aliases: AI663989; Fan1; Fascin; fascin-1; Fscn1; Snl
UniProt ID: (Rat) P85845, (Mouse) Q61553
Entrez Gene ID: (Rat) 683788, (Mouse) 14086
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