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Invitrogen
Dynactin 2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96095
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human DCTN2 (NP_0063911)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.55 mg/mL
规格
55 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HIIVNPNAAY DKFKDKRVGT KGLDFSDRIG KTKRTGYESG EYEMLGEGLG VKETPQQKYQ RLLHEVQELT TEVEKIKTTV KESATEEKLT PVLLAKQLAA LKQQLVASHL EKLLGPDAAI NLTDPDGALA KRLLLQLEAT KNSKGGSGGK TTGTPPDSSL VTYELHSRPE QDKFSQAAKV AELEKRLTEL ETAVRCDQDA QNPLSAGLQG ACLMETVELL QAKVSALDLA VLDQVEARLQ SVLGKVNEIA KHKASVEDAD TQSKVHQLYE T; Positive Samples: MCF7; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein, centrosome, cytoskeleton, microtubule organizing center
靶标信息
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
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