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Invitrogen
MYST1 Polyclonal Antibody
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MYST1 Antibody (PA5-96098) in WB
Western blot analysis of MYST1 in extracts of various cell lines. Samples were incubated with MYST1 Polyclonal antibody (Product # PA5-96098) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96098
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KAT8/MYST1/MOF (NP_8920032)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.76 mg/mL
规格
176 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MAAQGAAAAV AAGTSGVAGE GEPGPGENAA AEGTAPSPGR VSPPTPARGE PEVTVEIGET YLCRRPDSTW HSAEVIQSRV NDQEGREEFY VHYVGFNRRL DEWVDKNRLA LTKTVKDAVQ KNSEKYLSEL AEQPERKITR NQKRKHDEIN HVQKTYAEMD PTTAALEKEH EAITKVKYVD KIHIGNYEID AWYFSPFPED; Positive Samples: OVCAR3, NIH/3T3; Cellular Location: Chromosome, Nucleus
靶标信息
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3), yeast YBF2 and SAS2, and TIP60 (HTATIP). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: h FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase Myst1; Lysine acetyltransferase 8; Males-absent on the first protein homolog; mMof; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST protein 1; MYST-1; probable histone acetyltransferase MYST1; Protein acetyltransferase KAT8; Protein propionyltransferase KAT8
基因别名: 2010203C02Rik; 5830450F21Rik; D7Ertd629e; Kat8; MOF; Myst1
UniProt ID: (Mouse) Q9D1P2, (Rat) Q5XI06
Entrez Gene ID: (Mouse) 67773, (Rat) 310194
histone acetyltransferase activity
transcription factor binding
acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
enzyme binding
methylated histone binding
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
metal ion binding
histone acetyltransferase activity (H4-K16 specific)
molecular_function
histone modifying enzyme
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of autophagy
chromatin modification
histone acetylation
myeloid cell differentiation
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K16 acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
biological_process
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