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Invitrogen
LAMTOR5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-96186
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human LAMTOR5 (NP_0063932)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.07 mg/mL
Amount
207 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MEPGAGHLDG HRAGSPSLRQ ALCDGSAVMF SSKERGRCTV INFVPLEAPL RSTPRSRQVT EACGGEGRAV PLGSEPEWSV GGMEATLEQH LEDTMKNPSI VGVLCTDSQG LNLGCRGTLS DEHAGVISVL AQQAAKLTSD PTDIPVVCLE SDNGNIMIQK HDGITVAVHK MAS; Positive Samples: U-251MG, Mouse kidney; Cellular Location: Cytoplasm, Lysosome
Target Information
HBXIP, also named as XIP, belongs to the HBXIP family. It is originally identified by its interaction with the C-terminus of hepatitis B virus (HBV) X protein (HBx). HBXIP is a regulator of centrosome dynamics and cytokinesis. HBXIP is able to up-regulate S100A4 though activating STAT4 and inducing DNA methylation of PTEN. HBXIP is a cellular 18kd protein and cytoplasm stain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HBV X-interacting protein homolog; HBX-interacting protein homolog; hepatitis B virus x interacting protein; hepatitis B virus X-interacting protein homolog; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5; MGC71071; Ragulator complex protein LAMTOR5
Gene Aliases: 1110003H18Rik; Hbxip; Lamtor5; XIP
UniProt ID: (Mouse) Q9D1L9
Entrez Gene ID: (Rat) 295357, (Mouse) 68576
regulation of cell size
viral genome replication
positive regulation of TOR signaling
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
protein localization to lysosome
cellular response to amino acid stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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