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Invitrogen
Cyclophilin F Polyclonal Antibody
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Cyclophilin F Antibody (PA5-96237) in WB
Western blot analysis of Cyclophilin F in various lysates. Samples were incubated with Cyclophilin F Polyclonal antibody (Product # PA5-96237) using a dilution of 1:600, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96237
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 100-207 of human PPIF (NP_0057201)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.95 mg/mL
规格
95 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HepG2, B cells, Mouse kidney; Cellular Location: Mitochondrion matrix
Immunogen sequence: PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS
靶标信息
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cyclophilin D; Cyclophilin F; CyP-D; mitochondrial Cyclophilin D; mitochondrial peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase F; Peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; PPIase F; Rotamase F
基因别名: AW457192; CyP-D; CyP-F; CypD; PPIase; Ppif
UniProt ID: (Mouse) Q99KR7
Entrez Gene ID: (Mouse) 105675
protein peptidyl-prolyl isomerization
response to ischemia
protein folding
apoptotic process
response to oxidative stress
apoptotic mitochondrial changes
regulation of proton-transporting ATPase activity, rotational mechanism
regulation of necrotic cell death
programmed cell death
negative regulation of ATPase activity
regulation of apoptotic process
negative regulation of apoptotic process
regulation of mitochondrial membrane permeability
necroptotic process
cellular response to hydrogen peroxide
cellular response to arsenic-containing substance
cellular response to calcium ion
positive regulation of release of cytochrome c from mitochondria
negative regulation of release of cytochrome c from mitochondria
negative regulation of oxidative phosphorylation
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
negative regulation of oxidative phosphorylation uncoupler activity
negative regulation of intrinsic apoptotic signaling pathway
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