Invitrogen

PABPC4 Polyclonal Antibody

Name: PABPC4 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-96483
Availability: InStock

1 篇参考文献

查看其他12个PABPC4抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (4)

PABPC4 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 4

PABPC4 Antibody (PA5-96483) in ICC/IF

Immunofluorescence analysis of PABPC4 in U2OS cells. Samples were incubated with PABPC4 Polyclonal antibody (Product # PA5-96483) using a dilution of 1:100. Blue: DAPI for nuclear staining.

PABPC4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image PABPC4 Polyclonal Antibody

产品信息

PA5-96483

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

查看1篇已发表文章 1篇已发表文章

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

7 mg/mL

700 µg

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2808285

产品详细信息

Immunogen sequence: VTEMNGRIVG SKPLYVALAQ RKEERKAHLT NQYMQRVAGM RALPANAILN QFQPAAGGYF VPAVPQAQGR PPYYTPNQLA QMRPNPRWQQ GGRPQGFQGM P; Positive Samples: HepG2, Jurkat, Mouse spleen, Mouse heart, Rat brain, Rat heart; Cellular Location: Cytoplasm

靶标信息

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。