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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MELVQVLKRG LQQITGHGGL RGYLRVFFRT NDAKVGTLVG EDKYGNKYYE DNKQFFGRHR WVVYTTEMNG KNTFWDVDGS MVPPEWHRWL HSMTDDPPTT KPLTARKFIW TNHKFNVTGT PEQYVPYSTT RKKIQEWIPP STPYK; Positive Samples: 293T, PC-12, HepG2, Mouse kidney, Mouse heart, Mouse testis, Rat heart, Rat brain; Cellular Location: Matrix side, Mitochondrion inner membrane, Peripheral membrane protein
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 13 kDa differentiation-associated protein; 13kDa differentiation-associated protein; CI-B17.2; complex I B17.2 subunit; complex I-B17.2; DAP13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12-like; NADH-ubiquinone oxidoreductase subunit B17.2; unnamed protein product
基因别名: 2410011G03Rik; B17.2; CI-B17.2; CIB17.2; DAP13; MC1DN23; RGD1311462
UniProt ID: (Human) Q9UI09, (Mouse) Q7TMF3
Entrez Gene ID: (Human) 55967, (Mouse) 66414, (Rat) 299739