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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: FSGAVTRGRK VQKEGKISYA DFVWFLISEE DKKTPTSIEY WFRCMDLDGD GALSMFELEY FYEEQCRRLD SMAIEALPFQ DCLCQMLDLV KPRTEGKITL QDLKRCKLAN VFFDTFFNIE KYLDHEQKEQ ISLLRDGDSG GPELSDWEKY AAEEYDILVA EETAGEPWED GFEAELSPVE QKLSALRSPL AQRPFFEAPS PLGAVDLYEY ACGDEDLEPL; Positive Samples: HeLa, SW620, BT-474, SKOV3, mouse skeletal muscle; Cellular Location: Nucleus
Protein phosphatase 2 is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: NY-REN-8