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Invitrogen
SMEK1 Polyclonal Antibody
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SMEK1 Antibody (PA5-97089) in IHC (P)
Immunohistochemistry analysis of SMEK1 in paraffin-embedded human esophageal cancer. Samples were incubated with SMEK1 Polyclonal antibody (Product # PA5-97089) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-97089
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_0012712101)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.71 mg/mL
规格
71 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR TLEDEEEMWF NTDEDDMEDG EAVVSPSDKT KNDDDIMDPI SKFMERKKLK ESEEKEVLLK TNLSGRQSPS FKLSLSSGTK TNLTSQSSTT NLPGSPGSPG SPGSPGSPGS VPKNTSQTAA ITTKGGLVGL VDYPDDDEDD DEDEDKEDTL PLSKKAKFDS; Positive Samples: HeLa, HepG2, Jurkat, MCF-7, Mouse spleen, Rat brain; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center
靶标信息
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1
基因别名: 1110034C04Rik; BC064465; Kiaa2010; mKIAA2010; Pp4r3a; Ppp4r3a; RGD1309059; Smek1
UniProt ID: (Mouse) Q6P2K6
Entrez Gene ID: (Mouse) 68734, (Rat) 314388
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