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Invitrogen
TNPO1 Polyclonal Antibody
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FIGURE: 1 / 1
TNPO1 Antibody (PA5-97214) in WB
Western blot analysis of TNPO1 in extracts of various cell lines. Samples were incubated with TNPO1 Polyclonal antibody (Product # PA5-97214) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 1s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-97214
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 790-890 of human TNPO1 (NP_0022613)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.21 mg/mL
Amount
221 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: LO2, U-87MG, DU145, HeLa, Mouse kidney, Rat kidney; Cellular Location: Cytoplasm, Nucleus
Immunogen sequence: CPQEVAPMLQ QFIRPWCTSL RNIRDNEEKD SAFRGICTMI SVNPSGVIQD FIFFCDAVAS WINPKDDLRD MFCKILHGFK NQVGDENWRR FSDQFPLPLK E
Target Information
TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: importin 2; importin beta 2; importin beta-2; karyopherin (importin) beta 2; karyopherin beta-2; M9 region interaction protein; MAPKAP1; MSIN1; SAPK 1; SIN-1; SIN1; SIN1g; unnamed protein product
Gene Aliases: D13Ertd688e; IPO2; KPNB2; MIP; MIP1; TRN
UniProt ID: (Human) Q92973, (Mouse) Q8BFY9
Entrez Gene ID: (Human) 3842, (Mouse) 238799, (Rat) 309126
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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