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Invitrogen
NRXN1 Polyclonal Antibody
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NRXN1 Antibody (PA5-98362) in WB
Western Blot analysis of NRXN1 using a NRXN1 Polyclonal antibody (Product # PA5-98362) at a concentration of 1.57 µg/mL. Lane 1: Jurkat whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: HepG2 whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed band size: 162 kDa.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-98362
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Neurexin-1 protein (31-310AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.49 mg/mL
规格
49 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp313P2036; FLJ35941; Neurexin 1alpha; neurexin I; Neurexin I-alpha; Neurexin I-beta; Neurexin-1; Neurexin-1-alpha; Neurexin-1-beta; neuronal cell surface protein; unnamed protein product
基因别名: Hs.22998; KIAA0578; NRXN1; PTHSL2; SCZD17
Entrez Gene ID: (Human) 9378
transmembrane signaling receptor activity
receptor binding
type 1 fibroblast growth factor receptor binding
calcium channel regulator activity
calcium ion binding
protein binding
receptor regulator activity
acetylcholine receptor binding
signaling receptor activity
calcium-dependent protein binding
cell adhesion molecule binding
neuroligin family protein binding
angiogenesis
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
neuron cell-cell adhesion
signal transduction
chemical synaptic transmission
neurotransmitter secretion
nervous system development
axon guidance
synapse assembly
learning
positive regulation of gene expression
negative regulation of gene expression
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cerebellar granule cell differentiation
neuronal signal transduction
adult behavior
neuron projection development
positive regulation of synaptic transmission, GABAergic
social behavior
protein localization to synapse
vocal learning
establishment of protein localization
positive regulation of fibroblast growth factor receptor signaling pathway
neuron projection morphogenesis
neuromuscular process controlling balance
negative regulation of filopodium assembly
positive regulation of protein kinase B signaling
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
vocalization behavior
protein complex assembly involved in synapse maturation
positive regulation of synapse maturation
synaptic vesicle clustering
postsynaptic membrane assembly
presynaptic membrane assembly
gamma-aminobutyric acid receptor clustering
NMDA glutamate receptor clustering
gephyrin clustering involved in postsynaptic density assembly
guanylate kinase-associated protein clustering
neuroligin clustering involved in postsynaptic membrane assembly
postsynaptic density protein 95 clustering
receptor localization to synapse
NMDA selective glutamate receptor signaling pathway
AMPA selective glutamate receptor signaling pathway
trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
positive regulation of cAMP/PKA signal transduction
positive regulation of neuromuscular synaptic transmission
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of protein localization to plasma membrane
positive regulation of presynaptic active zone assembly
positive regulation of excitatory postsynaptic potential
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