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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes (PubMed:26475856). As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation (PubMed:21822278, PubMed:23335559). It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:19275885). Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: UBX domain containing 1; UBX domain-containing 2; UBX domain-containing protein 1; UBX domain-containing protein 6
基因别名: 1200008L11Rik; 2210415J11Rik; AU040909; Ubxd1; Ubxdc2; Ubxn6
UniProt ID: (Mouse) Q99PL6
Entrez Gene ID: (Mouse) 66530