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Invitrogen
ADNP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99221
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ADNP(Accession Q9H2P0), corresponding to amino acid residues I125-P175.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ADNP.
靶标信息
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activity-dependent neuroprotective protein; Activity-dependent neuroprotector homeobox protein
基因别名: AA589558; ADNP; ADNP1; KIAA0784; mKIAA0784
UniProt ID: (Mouse) Q9Z103
Entrez Gene ID: (Mouse) 11538
transcription, DNA-templated
regulation of transcription, DNA-templated
short-term memory
negative regulation of gene expression
regulation of protein ADP-ribosylation
positive regulation of neuron projection development
positive regulation of cGMP biosynthetic process
negative regulation of protein binding
activation of protein kinase activity
nitric oxide homeostasis
negative regulation of neuron apoptotic process
positive regulation of axon extension
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of synaptic transmission
positive regulation of synapse assembly
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