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Invitrogen
FOXH1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99223
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FOXH1(Accession O75593), corresponding to amino acid residues E165-P215.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total FOXH1.
靶标信息
FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fast-1; Fast-2; FAST1 transcription factor; Forkhead activin signal transducer 1; Forkhead activin signal transducer 2; Forkhead box protein H1
基因别名: fast-1; fast-2; FAST1; FAST2; FOXH1
UniProt ID: (Mouse) O88621
Entrez Gene ID: (Mouse) 14106
RNA polymerase II transcription cofactor activity
transcriptional activator activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
SMAD binding
androgen receptor binding
co-SMAD binding
R-SMAD binding
negative regulation of transcription from RNA polymerase II promoter
heart looping
secondary heart field specification
outflow tract morphogenesis
cardiac right ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transforming growth factor beta receptor signaling pathway
determination of left/right symmetry
anterior/posterior pattern specification
cell differentiation
negative regulation of intracellular estrogen receptor signaling pathway
embryonic heart tube anterior/posterior pattern specification
aorta morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
axial mesoderm development
negative regulation of androgen receptor signaling pathway
negative regulation of androgen receptor activity
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