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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total HOXD12.
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homeo box D12; Homeobox protein Hox-4.7; Homeobox protein Hox-4H; Homeobox protein Hox-5.6; Homeobox protein Hox-D12; Hox 4H
基因别名: Hox-4.7; Hox-5.6; HOX4H; Hoxd-12; HOXD12
UniProt ID: (Mouse) P23812
Entrez Gene ID: (Mouse) 15432