Invitrogen

HOXB5 Polyclonal Antibody

Name: HOXB5 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-99414
Availability: InStock

查看其他8个HOXB5抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

图: 1 / 1

HOXB5 Antibody (PA5-99414) in WB

Western blot analysis of HOXB5 in HUVEC cell lysate (left lane: treated with the antigen-specific peptide). Samples were incubated with HOXB5 polyclonal antibody (Product # PA5-99414).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

Immunogen image

Immunogen Image HOXB5 Polyclonal Antibody

产品信息

PA5-99414

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human HOXB5(Accession P09067), corresponding to amino acid residues T164-H214.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2818347

产品详细信息

Antibody detects endogenous levels of total HOXB5.

靶标信息

The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: homeo box B5; Homeobox protein H24.1; Homeobox protein HHO.C10; Homeobox protein Hox-2.1; Homeobox protein Hox-2A; Homeobox protein Hox-B5; Homeobox protein Hu-1; Homeobox protein Mu-1

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基因别名: AI385717; Hox-2.1; HOX2A; Hoxb-5; HOXB5

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UniProt ID: (Mouse) P09079

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Entrez Gene ID: (Mouse) 15413

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功能

RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding homeodomain transcription factor

参与通路

transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter multicellular organism development anterior/posterior pattern specification endothelial cell differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis embryonic skeletal system development