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Invitrogen
Phospho-LTK/ALK (Tyr672, Tyr1278) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-LTK/ALK (Tyr672, Tyr1278) Antibody (PA5-99574) in WB
Western blot analysis of Phospho-LTK/ALK (Tyr672, Tyr1278) in myeloma cells heat-shock treated (left lane: treated with blocking peptide). Samples were incubated with Phospho-LTK/ALK (Tyr672, Tyr1278) polyclonal antibody (Product # PA5-99574).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-99574
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human LTK(Accession P29376), corresponding to amino acid residues around phosphorylated Tyr672.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of LTK/ALK only when phosphorylated at Tyr672/Tyr1278.
Target Information
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anaplastic lymphoma receptor tyrosine kinase; CD246 antigen; leukocyte receptor tyrosine kinase; ltk; mutant anaplastic lymphoma kinase; npm-alk; protein tyrosine kinase 1; tyrosine kinase-1; unnamed protein product
Gene Aliases: ALK1; CD246; NBLST3; Tcrz; TYK1
UniProt ID: (Human) Q9UM73, (Mouse) P97793, (Human) P29376, (Mouse) P08923
Entrez Gene ID: (Human) 238, (Mouse) 11682, (Human) 4058, (Mouse) 17005
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell proliferation
positive regulation of cardiac muscle cell apoptotic process
positive regulation of neuron projection development
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
negative regulation of apoptotic process
regulation of neuron differentiation
positive regulation of protein kinase B signaling
cellular response to retinoic acid
response to stress
nervous system development
brain development
phosphorylation
hippocampus development
adult behavior
swimming behavior
protein autophosphorylation
negative regulation of lipid catabolic process
regulation of dopamine receptor signaling pathway
response to environmental enrichment
energy homeostasis
positive regulation of dendrite development
regulation of apoptotic process
neuron development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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