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Invitrogen
Phospho-LTK/ALK (Tyr672, Tyr1278) Polyclonal Antibody
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Phospho-LTK/ALK (Tyr672, Tyr1278) Antibody (PA5-99574) in WB
Western blot analysis of Phospho-LTK/ALK (Tyr672, Tyr1278) in myeloma cells heat-shock treated (left lane: treated with blocking peptide). Samples were incubated with Phospho-LTK/ALK (Tyr672, Tyr1278) polyclonal antibody (Product # PA5-99574).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99574
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LTK(Accession P29376), corresponding to amino acid residues around phosphorylated Tyr672.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of LTK/ALK only when phosphorylated at Tyr672/Tyr1278.
靶标信息
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; leukocyte receptor tyrosine kinase; Leukocyte tyrosine kinase receptor; npm-alk; Protein tyrosine kinase 1; tyrosine kinase-1
基因别名: ALK; CD246; LTK; Tcrz; TYK1
UniProt ID: (Mouse) P97793, (Mouse) P08923
Entrez Gene ID: (Mouse) 11682, (Mouse) 17005
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
identical protein binding
transmembrane signal receptor
activation of MAPK activity
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
phosphorylation
peptidyl-tyrosine phosphorylation
protein autophosphorylation
neuron development
cell proliferation
positive regulation of cardiac muscle cell apoptotic process
positive regulation of neuron projection development
phosphatidylinositol 3-kinase signaling
negative regulation of apoptotic process
cellular response to retinoic acid
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