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Invitrogen
CaV2.3 Polyclonal Antibody
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图: 1 / 3
CaV2.3 Antibody (PA5-99754) in ICC/IF
Immunofluorescent analysis of CaV2.3 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CaV2.3 polyclonal antibody (Product # PA5-99754) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99754
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CACNA1E(Accession Q15878), corresponding to amino acid residues S921-P971.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CACNA1E.
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BII; Brain calcium channel II; Calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; RBE-II; RBE2; voltage gated calcium channel alpha1E subunit; voltage-dependent calcium channel alpha1-E subunit; Voltage-dependent R-type calcium channel subunit alpha-1E; Voltage-gated calcium channel subunit alpha Cav2.3
基因别名: A430040I15; alpha1E; BII; CACH6; CACHA1E; CACNA1E; CACNL1A6; Cav2.3; Cchra1
Entrez Gene ID: (Rat) 54234, (Mouse) 12290
behavioral fear response
regulation of heart rate
calcium ion transport
chemical synaptic transmission
locomotory behavior
visual learning
transmission of nerve impulse
sensory perception of pain
sperm motility
regulation of ion transmembrane transport
glucose homeostasis
fear response
response to pain
behavioral response to pain
neurological system process
regulation of insulin secretion involved in cellular response to glucose stimulus
calcium ion import
calcium ion transmembrane transport
membrane depolarization during action potential
regulation of somatostatin secretion
transport
ion transport
transmembrane transport
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