'Protein microarrays represent an important new tool in proteomic systems biology. This review focuses on the contributions of protein microarrays to the discovery of novel disease biomarkers through antibody-based assays. Of particular interest is the use of protein microarrays for immune response profiling, through which a disease-specific antibody repertoire may ... More
Identification of new serum autoantibodies in neuromyelitis optica using protein microarrays.
AuthorsLalive PH, Menge T, Barman I, Cree BA, Genain CP,
JournalNeurology
PubMed ID16832107
Not Available
Protein microarray-based screening of antibody specificity.
The increased use of antibodies as therapeutics, as well as the growingdemand for large numbers of antibodies for high-throughput protein analyses, has been accompanied bya need for more specific antibodies. An array containing every protein for the relevant organism representsthe ideal format for an assay to test antibody specificity since ... More
A consolidated approach to analyzing data from high-throughput protein microarrays with an application to immune response profiling in humans.
Motivation: DNA microarrays are a well-known and established technology in biological and pharmaceutical research providing a wealth of information essential for understanding biological processes and aiding drug development. Protein microarrays are quickly emerging as a follow-up technology, which will also begin to experience rapid growth as the challenges in protein ... More