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Gibco
Human TNF-RII (soluble) Recombinant Protein
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产品信息
PHR3025
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Human TNF-RII recombinant protein contains 174 amino acids
分子量
18.9 kDa
分类
Recombinant
类型
Protein
纯度
≥98% by SDS-PAGE and HPLC
内毒素浓度
<0.1 ng/µg
活性
ED50 = 0.125 µg/mL; determined by the dose-dependent inhibition of TNF-alpha (0.25 ng/mL) mediated cytotoxicity in mouse L-929 cells.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
Amount
20 µg
纯化类型
purified
保存液
10mM sodium phosphate, pH 8, with 50mM NaCl
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute sTNF-RII in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C.
Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.
靶标信息
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 75-kda; CD120b; p75; p75 TNF receptor; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TNF-R2; TNF-RII; TNFR; TNFR II; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; Tumor necrosis factor receptor 2; tumor necrosis factor receptor protein (TNFR); Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor type II
基因别名: CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; TNFRSF1B
UniProt ID: (Human) P20333
Entrez Gene ID: (Human) 7133
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