Acute and long-term effects of IL-6 on cultured dorsal root ganglion neurones from adult rat.
Authorsvon Banchet GS, Kiehl M, Schaible HG
JournalJ Neurochem
PubMed ID15953366
IL-6 contributes to pain and hyperalgesia in inflamed tissue. We have investigated short- and long-term effects of IL-6 on dorsal root ganglion (DRG) neurones. Glycoprotein 130-like immunoreactivity (the signal transduction receptor subunit) was found in almost all neurones in DRG sections and in cultured DRG neurones from adult rat. In ... More