Lipopolysaccharide-induced changes in mesenteric afferent sensitivity of rat jejunum in vitro: role of prostaglandins.
AuthorsWang B, Glatzle J, Mueller MH, Kreis M, Enck P, Grundy D,
JournalAm J Physiol Gastrointest Liver Physiol
PubMed ID15790760
'Bacterial translocation across the intestinal mucosal barrier leads to a macrophage-mediated inflammatory response, visceral hyperalgesia, and ileus. Our aim was to examine how mediators released into mesenteric lymph following LPS treatment influence intestinal afferent sensitivity and the role played by prostanoids in any sensitization. Intestinal lymph was collected from awake ... More