Predictor™ hERG Fluorescence Polarization Assay Kit - Citations

Predictor™ hERG Fluorescence Polarization Assay Kit - Citations

View additional product information for Predictor™ hERG Fluorescence Polarization Assay Kit - Citations (PV5365)

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Abstract
Development of the predictor HERG fluorescence polarization assay using a membrane protein enrichment approach.
AuthorsPiper DR, Duff SR, Eliason HC, Frazee WJ, Frey EA, Fuerstenau-Sharp M, Jachec C, Marks BD, Pollok BA, Shekhani MS, Thompson DV, Whitney P, Vogel KW, Hess SD,
JournalAssay Drug Dev Technol
PubMed ID18471075
The life-threatening consequences of acquired, or drug-induced, long QT syndrome due to block of the human ether-a-go-go-related gene (hERG) channel are well appreciated and have been the cause of several drugs being removed from the market in recent years because of patient death. In the last decade, the propensity for ... More